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Journal of the Korean Wound Management Society 2005;1(1): 32-37. |
| 제품화된 폴리우레탄 드레싱제의 상피화 유도능 비교 |
| 한승규ㆍ김세현ㆍ이병일ㆍ김우경 |
| 고려대학교 의과대학 성형외과학교실 |
| Comparison of Polyurethane Foam Dressings on Inducing Wound Epithelialization |
| Seung-Kyu Han, Se-Hyun Kim, Byung-Il Lee, Woo-Kyung Kim |
| Department of Plastic Surgery, Korea University College of Medicine, Seoul, Korea |
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Published online: 30 November 2005. |
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| ABSTRACT |
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Polyurethane foam dressings are becoming widely used in partial and full thickness skin wounds since they are safe and convenient to patients and physicians. However, the influence of polyurethane foam dressings on epithelialization has not been fully determined yet. This study was designed to compare two internationally available polyurethane foams and three locally made polyurethane foams as to their effects on the epithelialization in vivo. Twentywhite rats were used. A 5 mm punch was employed to excise skin and subcutaneous tissue in a round fashion at six sites on the back area of 10 rats. After creating 6 open wounds, above mentioned 5 polyurethane foams and gauze dressings were applied. On the 5th day the lengths of the nonepithelialized area were measured under light microscope. In addition, partial thickness wounds were created using carbon dioxide laser at six sites on the back of the another 10 rats. Six dressings were applied on the wounds as same as above. On the 4th day the degree of the epithelialization was measured and compared. In full thickness wound study the best wound closing was also seen in chitin mixed Medifoam-N group. In partial thickness wound study the best epithelialization was seen in chitin mixed Medifoam-N and chitosan mixed Medifoam-N groups. These results demonstrated that polyurethane foam dressings influenced the epithelialization, and chitin mixed Medifoam-N showed the best result. (J Korean Wound Care Soc 2005;1:32-37) |
| Key Words:
Polyurethane foam dressing, Epithelialization |
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