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J Korean Wound Management Soc > Volume 4(2); 2008 > Article
Journal of the Korean Wound Management Society 2008;4(2): 96-104.
창상치료용 생체조직 접착제의 최근 연구개발 동향
한국과학기술연구원 바이오소재연구센터
Recent Trend of Research and Development in Biological Tissue Adhesives for Wound Care
Dong Keun Han, Kwideok Park, Jae-Jin Kim
Biomaterials Research Center, Korea Institute of Science and Technology, Seoul, Korea
  Published online: 30 November 2008.
Tissue adhesives have been widely utilized for sealing, immobilization, and adhesion of biological tissues and organs. Their use can be divided into two categories such as soft and hard tissues according to application parts. In particular, the former for wound care includes cyanoacrylate instant adhesive, fibrin glue, protein glue, polyurethane adhesive, polyethylene glycol (PEG) sealant, marine mussel adhesive, etc. Among them, Dermabond, 2-octyl cyanoacrylate, was approved by the FDA as a topical skin adhesive and thus it is expected to be extended to apply for wound closure and sealing of surgical incisions. This review deals with the recent trend of R&D in tissue adhesives and their characteristics and uses in wound care. (J Korean Wound Management Soc 2008;4:96-104)
Key Words: Tissue adhesives, 2-Octyl cyanoacrylate, Fibrin glue, Protein adhesive, Mussel adhesive
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