Electrospun Nanofibers as Wound Dressing Materials

J Korean Wound Management Soc > Volume 3(2); 2007 > Article

Original

Journal of the Korean Wound Management Society 2007;3(2): 63-72.

창상 드레싱재로서의 전기방사 나노섬유

조완진ㆍ오세행ㆍ이진호

한남대학교 생명ㆍ나노과학대학 신소재공학과

Electrospun Nanofibers as Wound Dressing Materials

Wan Jin Cho, Se Heang Oh, Jin Ho Lee

Department of Advanced Materials, College of Life Science & Nano Technology, Hannam University, Daejeon, Korea

Published online: 30 November 2007.

ABSTRACT

Electrospinning is a simple fabrication process that can produce nonwoven sheet, highly porous nanometer-scale fiber-based matrices using an electrostatically driven jet of polymer solution or melt. The nanofibers fabricated by electrospinning technique have caught much attention as the most promising stuffs for biomedical applications because of their ability to mimic the nano-scaled geometry and topology of native extracellular matrix (ECM) structures, which may retain mechanical strength, flexibility, and high porosity. Recently, the nanofibrous nonwoven sheets have been suggested as good wound dressing materials due to their high gas permeation and effective protection of the wound from infection and dehydration. In this review article, we introduced various studies related to the wound healing using electrospun nanofibers as a wound dressing materials and also discussed their properties, research trend, and development directions. (J Korean Wound Care Soc 2007;3:63-72)

Key Words: Wound dressing, Electrospinning, Nanofiber